This volume provides and educative and authoriative discussions on the drug discovery and development process. It is divided into ten sections and starts with personal recollections on the history and evolution of the drug discovery process. To illustrate the end result of the drug discovery process, a large chapter reviews the major drug introductions over 1993-2003. Subsequent chapters examine the impact of genomic technologies, new sources of drugs and alternatives to animal testing. The next section reviews the roles of enterprise and pharamaceuticals companies, venture capitalists and academic-industrial relations in the drug discovery process. Social and ethical issues are reviewed in the context of assessing health demands in developed, developing countries and also in relation to smaller scale diseases (orphan drugs). Two chapters then review the bioethical and ethical issues facing the pharmaceutical industry. The volume concludes with reviews on funding and regulartion and how intellectual property rights and patents are protected. With such a wide variety of topics this volume will appeal to both scientists and non-scientists who need to understand how and why the pharmaceutical industry works.
* valuable content available from May 2009 as an individual volume * provides a global overview of the drug discovery process
J. P. Pearson , K. M. Gray , L. Passador , K. D. Tucker , A. Eberhard , B. H. Iglewski , and E. P. Greenberg , Proc . Natl . Acad . Sci . USA , 1994 , 91 , 197 . 94. J. P. Pearson , L. Passador , B. H. Iglewski , and E. P. Greenberg ...
rubber subjected to the following thermal treatments : cool rapidly to – 40 ° C , hold for 24 hr ; raise rapidly to – 5 ... Bryant 1947. W. M. D. Bryant , “ Polythene Fine Structure , ” J. Polym . Sci . 2 , 547–564 ( 1947 ) . Bunn 1953.
感谢尼尔·斯蒂芬斯为本书设计了漂亮的封面和插图。朱丽娅·珀西瓦尔不仅为本书制作了出色的图表,而且阅读了我的文稿并对开头的几章提出了自己的意见,感谢你超出职责范围的额外贡献。大英图书馆的工作人员都是热心人,尤其是科技类阅览室的。
飞鸟、奈良、平安时代:日本香道初发展兰奢待,日本现存最大的沉香处于隋唐时期的日本也出现了其历史上的第一块沉香。据《日本书记》记载,“推古三年(公元595年,隋文帝开皇十五年)有沈木(指沉香木)漂于淡路岛(日本本州与四国之间,濑户内海中),其大一围, ...
This volume covers the three main transport process of interest to chemical engineers - momentum transfer (fluid flow), heat transfer and mass transfer and the relationships between them.
Chemical Engineering: Solutions to the problems in Chemical engineering, vol. 1
Krieger , Gary R. and Ian Austin . 1995. “ International Legal and Legislative Framework . ” Accident Prevention Manual for ... Miller , Jeffrey G. 1985. “ Marine Protection , Research and Sanctuaries Act . ” Environmental Law Handbook ...
The latest edition of the bestselling Groundwater Chemicals Desk Reference contains double the amount of data found in the original edition. Hundreds of chemicals and chemical compounds are easily located in this latest edition.
P. Allen and D. J. Tildesley , Computer Simulation of Liquids , Clarendon Press , Oxford , 1989 ; D. Frenkel and B. Smit , Understanding Molecular Simulations : From Algorithms to Applications , Academic Press , San Diego , 1996 .
''Bottom line: For a holistic view of chemical engineering design, this book provides as much, if not more, than any other book available on the topic.' Extract from Chemical Engineering...