The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style
This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove ...
Biotechnol. Bioeng., 16, 99. Kohen, A. (2006). In A. Kohen, & H.-H. Limbach (Eds.), Isotope Effects in Chemistry and Biology (p. 744). Boca Raton, Florida: Taylor and Francis. Kohen, A., & Klinman, J. P. (1999). Chem. Biol., 6, R191.
124 J. F. Bunnett , J. H. Miles , and K. V. Nahabedian , J. Am . Chem . Soc . 83 , 2512 ( 1961 ) . 125 E. Pfeil , H. Stache , and F. Lömker , Ann . Chem . 623 , 74 ( 1959 ) . 125 R. G. Pearson , D. H. Anderson , and L. L. Alt , J. Am ...
This book is designed for students of biology, molecular biology, ecology, medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays the important role.
This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals.
Herbert M. Sauro. [38] Karp, P. D., I. M. Keseler, A. Shearer, M. Latendresse, M. Krum- menacker, S. M. Paley, I. Paulsen, J. Collado-Vides, S. Gama- Castro, M. Peralta-Gil, ... [49] Monod, J., J Wyman, and J. P. Changeux. 1965.
Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data.
For the second edition of 'Microreactors in Organic Chemistry and Catalysis' all chapters have been revised and updated to reflect the latest developments in this rapidly developing field.
Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive ...
Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind ...