Until recently, the traditional model of pharmaceutical research had been applied to programs of genetic study, resulting in the many therapeutic agents either under developed or in clinical usage. However, a shift in emphasis is currently taking place towards the so-called "Genome Projects" which enable the identification of gene sequences on a much larger scale and have established gene therapy as a more viable route to treatment. They have also forced pharmaceutical research to its "watershed". Genomes, Molecular Biology, and Drug Discovery is based on the 7th SmithKline Beecham International Symposium and attempts to bring the continuing advances in modern genome research and molecular biology together with new pharmacological and chemical strategies sharply into focus. It highlights the need for a multi-disciplinary approach in order to direct the wealth of information accumulated towards better community healthcare and close the drug discovery loop. Genome Projects * Interpreting the Code * From Gene to Target * From Target to Therapy * Conclusions and Challenges