An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building
The book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.
This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.
This volume is a compilation of extended abstracts of all papers presented at the 14th International Plant Nutrition Colloquium.
The emphasis of this book is, therefore, on experimental methods for resolving the kinetics and dynamics of pumps, channels, and transporters.
Channels and Pumps" Inaugurates the third decade of the Jerusalem Symposia. It enlarges substantially their conceptual scope by Introducing a new subject not treated there previously. In fact.
This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and ...
Membrane transport proteins are crucial to maintain homeostasis and assure cell survival upon intracellular or environmental stress. A failure of any of these transport systems may have dramatic consequences for cell function.
A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom.
Indeed, as we have seen in the previous two sections, the transporter exists as a free molecule, as a molecule binding one ion and as a molecule binding both ions. Among many possible models, experimental data will dictate the viable ...
Due to their vital involvement in a wide variety of housekeeping and specialized cellular functions, exocytosis and endocytosis remain among the most popular subjects in biology and biomedical sciences.