Pediatric Neurology: Chapter 128. Neurological expression of genetic immunodeficiencies and of opportunistic infections
- ISBN-10
- 0128079290
- ISBN-13
- 9780128079294
- Series
- Pediatric Neurology
- Category
- Medical
- Pages
- 544
- Language
- English
- Published
- 2013-04-23
- Publisher
- Elsevier Inc. Chapters
- Authors
- Tardieu Marc, Rostasy Kevin
Description
Immunodeficiencies may result from genetic defects or may be acquired after viral infection or therapeutic immunosuppression. In either case, neurological symptoms are frequent. Hemophagocytic lymphohistiocytosis (HLH), previously designated as macrophage activation syndrome (MAS), results usually from genetic defects impairing the cytotoxicity of CD8 T lymphocytes and natural killer (NK) cells. Neurological symptoms may be the first and only manifestation of the disease. The neurological and neuroradiological aspects of MAS, if isolated, may closely resemble those of other central nervous system (CNS) diseases such as acute disseminated encephalomyelitis (ADEM) or encephalitis. An early treatment including allogeneic hematopoietic stem cell transplantation can prevent further brain lesions. The main infections of the CNS observed in conjunction with therapeutic immunosuppression are described. It is important to know which phase of immunosuppression the child is in at the time of suspected CNS infection and always to consider that a relapse of the primary tumor may mimic a CNS infection.
Get the book
Other editions
-
- 2013-04-23
- 544 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-04-23
- 544 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-04-23
- 544 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-04-23
- 544 pages
- Ebook
- Elsevier Inc. Chapters
Similar books
-
How Institutions are Shaping the Future of Our Children: For Better or for Worse?
By Catherine Dulmus, Karen SowersLammert, M., & Timberlake, E. M. (1986). Termination of foster care for the older adolescent: Issues of emancipation and individuation.
-
Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity
By William J. Rea, Kalpana D. PatelDou, L., E. Bertrand, C. Cerini, V. Faure, J. Sampol, R. Vanholder, Y. Berland, P. Brunet. ... A. Timberlake, B. Sumpio, R. Pfragner, I. M. Modlin, M. Kidd.
-
Rockwood and Green's Fractures in Adults
By William Ricci, Charles M. Court-Brown, Margaret M. McQueenChendrasekhar A, Moorman DW, Timberlake GA. An evaluation of the effects of ... Chittiboina P, Wylen E, Ogden A, et al. Traumatic spondylolisthesis of the ...
-
Breast Pathology, An Issue of Surgical Pathology Clinics
By Laura C. CollinsHartmann LC, Radisky DC, Frost MH, et al. Understanding the premalignant potential of ... D'Alfonso TM, Wang K, Chiu YL, et al. Pathologic upgrade rates on ...
-
Telepractice in Speech-Language Pathology
By K. Todd HoustonStensland, J., Speedie, S., Ideker, M., House, J., & Thompson, T. (1999). The relative cost of outpatient ... Deal, J. L. (1987). Appraisal and diagnosis of ...
-
Addressing Adversity: Prioritising adversity and trauma-informed care for children and young people in England.
By Marc Bush, Lord Victor Adebowale, Rebecca Adlington1 2 Howard, S. and Johnson, B. (2000) Resilient and Non-resilient Behaviour in ... 4 De Haan, L., Hawley, D. and Deal, J. (2002) 'Operationalizing family ...
-
Culture, Brain, and Analgesia: Understanding and Managing Pain in Diverse Populations
By Mario Incayawar, Knox H. Todd... are not fluent in the language/s of the medical care provider.72 Research ... Anglo-Americans have traditionally placed a great deal of emphasis on the ...
-
Image-Guided Spine Interventions
By John M. MathisThis practical guide thoroughly discusses both well-established and new interventions that are applied to the spine for the purpose of pain relief.
-
New Mynursinglab -- Access Card -- For Maternal-Child Nursing (24-Month Access)
By Pearson Education, Pearson Education, Inc., David P Pearson EducationSeveral versions of Pearson's MyLab & Mastering products exist for each title, including customized versions for individual schools, and registrations are not transferable.
-
Pearson's Medical Assisting (General)
By Pearson Education Staff, Madan Dr Pearson EducationIf a picture paints a thousand words, imagine what video can do? Pearson Medical Assisting Videos help users learn the nuances and the details of many medical assisting procedures.