Neuroparasitology and Tropical Neurology: Chapter 3. Immunodiagnosis of CNS parasitic infections

Neuroparasitology and Tropical Neurology: Chapter 3. Immunodiagnosis of CNS parasitic infections
ISBN-10
0128079479
ISBN-13
9780128079478
Series
Neuroparasitology and Tropical Neurology
Category
Medical
Pages
432
Language
English
Published
2013-07-03
Publisher
Elsevier Inc. Chapters
Author
Patricia P. Wilkins

Description

The nature of many parasitic infections of the central nervous system (CNS) requires immunodiagnosis to confirm presumptive diagnoses. The CNS is the primary site of parasite infection for some parasitic organisms and for others, neurological infection occurs only in immunocompromised hosts. Still other parasites cause ectopic infections of the CNS and occur very rarely. This review concentrates on laboratory diagnosis of diseases that are caused by parasites with a primary predilection for the CNS. Emphasis is placed on laboratory diagnostic methods that are used and suitable for clinical diagnosis, rather than a comprehensive review of all the experimental methods that have been reported in the literature. Immunodiagnosis is not appropriate for the diagnosis of all parasitic infections of the CNS; in those cases, alternative diagnostic methods are presented, but not discussed in detail. In some instances potential new antigens or methods are presented, particularly if adoption of these methods is expected in the near future.

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