Sex and Gender Differences in Alzheimer's Disease
- ISBN-10
- 012819345X
- ISBN-13
- 9780128193457
- Category
- Medical
- Pages
- 512
- Language
- English
- Published
- 2021-07-23
- Publisher
- Academic Press
- Authors
- Maria Teresa Ferretti, Annemarie Schumacher Dimech, Antonella Santuccione Chadha
Description
Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease. This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Provides a comprehensive and critical review of sex differences in Alzheimer’s disease Features discussion of sex and gender differences in disease biology, treatment, and socioeconomic factors, including impact on caregivers Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists, policymakers, health scientists, and clinical trial experts, for a 360-degree view on the topic and its possible implications Edited by the Women’s Brain Project, the leading NGO in the field of sex and gender differences in brain and mental health as the gateway to precision medicine
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