In this provocative book on the process of growing old, Michael Rose goes right to the heart of the fundamental "unsolved problem" of biology. Why do we grow old? The proposed theory is that to understand aging we must understand its evolution; only then do its taxonomic distribution and its genetic and physiological mechanisms become intelligible. Evidence is produced from the fields of cell biology, physiology, and gerontology.
Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.
The author of this monograph proposes an evolutionary theory of senescence - that the force of natural selection declines proportionally with age after the onset of reproduction.
The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new ...
The book ranges from Rose's first experiments while a graduate student--counting a million fruit fly eggs, which took 3,000 hours over the course of a year--to some of his key scientific discoveries.
Does Aging Stop? shatters the conventional beliefs on which aging research has been based for the last fifty years.
... P. B. Gray, S. M. Kahlenberg, E. S. Barrett, S. F. Lipson, and P. T. Ellison, “Marriage and Fatherhood Are Associated with Lower Testosterone in Males,” Evolution and Human Behavior 23 (2002): 193–201; P. B. Gray, J. C. Parkin, ...
In: Scanes, C.G. & Schriebman, M.P. (Eds.) Development, Maturation & Senescence of the Neuroendocrine System. Academic Press, pp. 223-252. - Mobbs, C.V., 1990. Neurotoxic effects of estrogen, glucose, and glucocorticoids: Neurohumoral ...
Vitamin E regulates mitochondrial hydrogen peroxide generation. ... Clancy, D. J., D. Gems, L. G. Harshman, S. Oldham, H. Stocker, E. Hafen, S. J. Leevers and L. Partridge. ... Cohn, L., A. G. Feller, M. W. Draper, I. W. Rudman and ...
Egocentricity is characteristically human.
In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals.