Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path
This textbook serves as a comprehensive reference on the latest science underlying the development of biological therapies, as well as their use in animal and human studies of rheumatological disease.
This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Pauzner R, Mayan H, Hershko E, Alcalay M, Farfel Z. Exacerbation of Wegener's granulomatosis during pregnancy: report ... Roux CH, Brocq O, Breuil V, Albert C, Euller-Ziegler L. Pregnancy in rheumatology patients exposed to anti- tumour ...
... rheumatoid arthritis. Pharmacoeconomics 22: 1–12. 2. Vital, E.M. & P. Emery. 2008. The development of targeted therapies in rheumatoid arthritis. J. Autoimmun. 31: 219–227. 3. Firestein, G.S. 2003. Evolving concepts of rheumatoid ...
Matthews C, Coakley G, Field M et al. BSR & BHPR, BOA, RCGP &BSAC Guideline for management of the hot swollen joint in adults. Rheumatology 2006;45:1039–1041. McGillicuddy DC, Shah KH, Friedberg RP, Nathanson LA, ...
This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease.
... D.M.; Williams, D.R. Trace element medicine and chelation therapy. The Royal Society of Chemistry: Cambridge, 1995. [2] Klasco, R.K., Ed. POISINDEX® System, Thomson Healthcare, Greenwood Village, CO, Edition expires 9/2008.
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Sieper, J., Koenig, A., Baumgartner, S., Wishneski, C., Foehl, J., Vlahos, B., Freundlich, B. (2010). Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials. Ann Rheum Dis, 69(1), 226–229.
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible ...