Multidisciplinary perspectives and approaches to quinone methides research The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. This inaugural volume in the series, Quinone Methides, represents the first book devoted to this fascinating and useful intermediate. The authors of this work reflect the many disciplines and approaches to quinone methides research. The volume therefore covers a broad range of topics, including theoretical treatments, generation and detection of intermediates, characterization and applications in chemistry and biochemistry, and biological reactivity. Among the chapters are: Photochemical generation and characterization of quinone methides Quinone methide stabilization by metal complexation Self-immolative dendrimers based on quinone methides Characterization of quinone methides by spectral global fitting and 13C labeling Formation and reactions of xenobiotic quinone methides in biology Quinone methides in lignification With this collection of topics, readers already familiar with quinone methides have the opportunity to advance their own research by discovering new inspiration and opportunities in allied areas. Moreover, the range of topics and perspectives covered make this volume accessible to readers with a broad range of interests, including organic and physical chemistry, biochemistry, biotechnology, and pharmaceutics.
This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
This volume focuses on explorative activity-based proteomics, biomedical applications of activity-based proteomics, and chemical strategies in activity-based proteomics providing a concise overview of activity-based protein profiling.
Moreover, ARmediated mechanisms play a critical role in the regulation of the ovulatory processes as AR-null females have reduced ovulation rates and expression of Ptgs2 and Areg, which are known to stimulate ovulation in response to ...
Chem Commun 2003:1400–1. Shiomi D, Nozaki M., Ise T, Sato K, Takui T. J. Phys Chem B 2004;108:16606–8. Das K, Pink M, Rajca S, Rajca A. JAm Chem Soc 2006; 128:5334–5. (a) Aso M, Ikeno T, Norihisa K, Tanaka M, Koga N, Suemune H. J. Chem ...
This is an organic chemistry reference work, focusing on reactions that add a C-1 unit to a substrate.
of NADA to NADA quinone methide, but subsequent experiments proved that it is a two-step reaction and led to the ... methides are isomers of 4-alkyl substituted quinones and they are more reactive than conventional quinone counterparts ...
An appendix with selected experimental details for benign and straight-forward procedures rounds of the book, making this the number-one information source for organic chemists in academia and industry.
This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier ...
Hydroxybenzophenone 64 oxidizes into (alkylperoxy)cyclohexadienone 228, substituted benzoquinone 229, and xanthone 230 (30,38). ... Hydroxybenzophenones, therefore, are rather ineffective photostabilizers in high-impact polystyrene or ...
The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended.