Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.
... in medicine. Polyphosphazene synthesis poses many more challenges than other standard polymers, for example, for ... polyphosphazenes (see Chapter 2) could be significant for medical applications, as biodegradable polymers with the ...
Harry Allcock’s Chemistry and Applications of Polyphosphazenes provides the only published compilation of material on polyphosphazenes, detailing synthetic methodologies and physical properties for each substance.
A symposium titled "Polyphosphazenes in Biomedicine, Engineering & Pioneering Synthesis" was held at a recent meeting of the American Chemical Society (ACS) in August 2017 in Washington, DC. The chapters in this book provide a summary of ...
Hargreaves, J. S.; Webber, S. E. Polym. Photochem. 1982, 2, 359. 48. Yeung, A. S.; Frank, C. W.; Singler, R. E. ACS Polym. Prep. 1986, 27(2), 214. 49. Yeung, A. S.; Frank, C. W.; Singler, R. E. Polymer 1990, 31, 1092. 50.
Written by expert researchers in the chemistry of phosphorus-containing polymers, this book is suitable for academic and industrial researchers interested in polymer and materials synthesis as well as their applications.
Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field.
With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications.
This book describes preparation techniques for well-defined, customizable poly(organo)phosphazene materials and their applications in nanomedicine, i.e. as macromolecular carriers for drug delivery, immunology, gene therapy, or tissue ...
Polyphosphazenes in Biomedicine, Engineering, and Pioneering Synthesis
The main aim of this book is to provide a complete picture of current research on phosphazene compounds carried out around the world.