Dog Pals border collies, Sophie (the leader and brave one) and Wallace (the spazzy goof-ball) along with their best bud chocolate lab mix Sulley (the uptight over-thinker) were born into a post-apocalyptic world populated by anthropomorphic animals. After their parents mysteriously disappeared when they were young, the pups were raised by their wacky but wise grandmother, Memuzzer, who still guides, inspires, and patches their flight suits. The dog pals now run a successful helicopter business (Fly Dogs) out of their jungle tree-fort in their secluded jungle town, but occasionally they have to drop everything to go save the world.