This book is a practical guide for those engaged in small-molecule com binatorial chemistry as well as those wishing to learn the field. Aime d at nonspecialists, the chapters are written in a tutorial style by i nternationally recognized experts. The text reviews the use of computa tional tools to analyze molecular diversity and presents a detailed su rvey of solid-phase peptide synthesis and the tools used for small-mol ecule synthesis. Up-to-date automated approaches and equipment for syn thesizing solid- and solution-phase libraries are reviewed, including synthesis, analytical, and deconvolution tools. This book will be usef ul to medicinal chemists, organic chemists, biochemists engaged in hig h-throughput screening, materials scientists, patent professionals, an d science writers.