Target Organ Toxicity, Volume I
- ISBN-10
- 1000714543
- ISBN-13
- 9781000714548
- Category
- Medical
- Pages
- 242
- Language
- English
- Published
- 2020-01-29
- Publisher
- CRC Press
- Author
- Gerald M. Cohen
Description
This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
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