The replacement of hydrogen with fluorine in organic molecules can profoundly influence their chemical and physical properties, leading to a range of compounds with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, so that organofluorine chemistry is economically highly important. Organofluorine Chemistry will help chemists to develop a systematic knowledge of the chemistry of fluorine with a view towards its application in the design of new reactions and syntheses, and the creation of novel fluorinated molecules and materials. With initial chapters focusing on why fluorine creates such unique properties in organic compounds, the book then covers general reactions of fluorine. Coverage is chosen from the recent research literature, concentrating on the development of novel bioactive compounds and catalytic ligands, and explaining, in the context of the initial chapters, how and why fluorine is so effective. With a final chapter covering the general synthetic chemistry of organofluorine compounds, the book is a cohesive summary of the fundamental principals of organofluorine chemistry.
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2,628,989 (1953) to Allied Chemical [CA48, 1406 (1954)]; O. Scherer, A. Steinmetz, H. Kuhn, W. Wetzel, and K. Grafen, U.S. Pat. 3,183,277 (1965) to Hoechst [CA55, 12295 (1961)]. C. F. Feasley and W. H. Stover, U.S. Pat.
Organofluorine Compounds in Biology and Medicine. Elsevier, Amsterdam. G. Haufe and F. Leroux (2019). Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals, Progress in Fluorine Science Series, Vol.
In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described.
In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described.
In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and ...
Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways.
In this book, we have gathered authors with immense experience in various aspects of their field and each is a world-authority on the important topics they have described.
"The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating ...
This book covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems.