Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.
... rats. In this regard, nitric oxide has been shown to promote relaxation of skeletal muscle through the cGMP pathway ... rat: the parotid gland; the submaxillary or submandibular salivary glands; and the sublingual glands. The parotid ...
This guide was created especially for individuals performing research with rats whose duties include animal facility management, animal husbandry, regulatory compliance, and technical procedures involved with their research.
Fuchs, H., Gailus-Durner, V., Adler, T., Aguilar—Pimentel, J . A., Becker, L., Calzada—Wack, J ., Da Silva—Buttkus, P., Neff, F., Gotz, A., Hans, W., Holter, S. M., Horsch, M., Kastenmuller, G., Kemter, E., Lengger, C., Maier, H., ...
The first part of this book retraces the biomedical history of early events and personalities involved in the establishment of rats as a leading laboratory animal. The taxonomy, genetics and inbred strains of rats are also elaborated.
In: Baker, H.J., Lindsey, J.R. and Weisbroth, S.H. (eds). The Laboratory Rat, Vol. 1, pp. 1–36. ... Meng, J., Wyss, A.R., Dawson, M.R. and Zhai, R. (1994) Nature 370, 134–136. Philipeaux (1856) C. R. Hebd Seances.Acado.43,904–906.
The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals.
This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields.
These 14 volumes are compact and comb-bound to lay flat for use in the laboratory.
The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs.
[68] Mahadeva R, Shapiro SD. ... [77] Heinrich U, Fuhst R, Peters L, Muhle H, Dasenbrock C, Pott F. Comparative longterm animal inhalation studies using various particulate ... [81] Larsen ST, Roursgaard M, Jensen KA, Nielsen GD.