Drug Metabolism and Pharmacokinetics Quick Guide
- ISBN-10
- 1441956298
- ISBN-13
- 9781441956293
- Category
- Medical
- Pages
- 214
- Language
- English
- Published
- 2011-04-07
- Publisher
- Springer Science & Business Media
- Authors
- Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E.C.A. Hop
Description
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
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