Computational Methods for Three-Dimensional Microscopy Reconstruction

Computational Methods for Three-Dimensional Microscopy Reconstruction
ISBN-10
1461495210
ISBN-13
9781461495215
Category
Mathematics
Pages
260
Language
English
Published
2014-01-29
Publisher
Springer Science & Business Media
Authors
Joachim Frank, Gabor T. Herman

Description

Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ in detail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology. Computational Methods for Three-Dimensional Microscopy Reconstruction will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in the area of 3D imaging and modeling.

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