The pharmacology, overdoses, and poisonings section from Irwin and Rippe's Manual of Intensive Care Medicine, Fourth Edition, has now been expanded into a complete, stand-alone SpiralĀ® Manual. This new Manual of Overdoses and Poisonings is a practical quick-reference bedside guide to the evaluation and treatment of toxic or potentially toxic drug and chemical exposures. The first chapter presents a general approach to differential diagnosis, diagnosis, and treatment of poisoning. Subsequent chapters focus on specific drugs, chemicals, and toxidromes and provide details on clinical presentation.