Bioconjugation: Methods and Protocols
- ISBN-10
- 1493996541
- ISBN-13
- 9781493996544
- Category
- Biochemistry
- Pages
- 317
- Language
- English
- Published
- 2019
- Authors
- Sam Massa, Nick Devoogdt
Description
This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an antibody-drug conjugate, an optical probe, a nanomedicine, or a radiopharmaceutical. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bioconjugation: Methods and Protocols is an ideal guide for researchers looking toward precision medicine in order to expand the vital field of drug discovery.
Get the book
Similar books
-
General, Organic, and Biological Chemistry Study Guide and Selected Solutions: Structures of Life
By Karen C. TimberlakeKeyed to the learning goals in the text, this guide is designed to promote active learning through a variety of exercises with answers and mastery exams. The guide also contains complete solutions to odd-numbered problems.
-
Study Guide with Selected Solutions for General, Organic and Biological Chemistry: Structures of Life
By Karen C. TimberlakeKeyed to the learning goals in the text, this guide is designed to promote active learning through a variety of exercises with answers and mastery exams. The guide also contains complete solutions to odd-numbered problems.
-
Química general, orgánica y biológica: estructuras de la vida
By Karen C. TimberlakeQuímica general, orgánica y biológica: estructuras de la vida
-
General, Organic, and Biological Chemistry, Loose-Leaf Edition
By Laura D. Frost, S. Todd DealIf you would like to purchase both the loose-leaf version of the text and Mastering Chemistry, search for: 0135188644 / 9780135188644 General, Organic, and Biological Chemistry, Loose-Leaf Plus Mastering Chemistry with Pearson eText -- ...
-
Laboratory Manual for General, Organic, and Biological Chemistry
By S. DealMany of the experiments illustrate concepts from more than one chapter of the text and often utilize basics from the areas of general, organic, or biological chemistry to develop concepts in one or more of the other areas.
-
Carbohydrate Chemistry and Biochemistry: Structure and Mechanism
By Michael SinnottD. M. A. Guerin, M. B. Lascombe, M. Costabel, H. Souchon, V. Lamzin, P. Beguin and P. Alzari, J. Mol. Biol., 2002, 316, 1061. 117. ... A. Varrot, J. McDonald, R. V. Stick, G. Pell, H. J. Gilbert and G. J. Davies, Chem.
-
Introduction to Organic & Biochemistry
By Frederick A. Bettelheim, William Henry Brown, Jerry MarchCD-ROM contains tutorial multimedia modules; molecular models.
-
Cantarow and Trumper, Clinical Biochemistry, with a Chapter on Hormone Assay and Endocrine Function
By Abraham Cantarow, Albert L. Latner, Max TrumperMerritt , H. H. , and Fremont - Smith , F .: The Cerebrospinal Fluid . Philadelphia , W. B. Saunders Co. , 1937 . Wolf , P. L. , Williams , D. , and Von der Muehll , E .: Practical Clinical Enzymology and Biochemical Profiling ...
-
Atkins' Physical Chemistry
By Peter William Atkins, Julio De Paula, James Keeler(5A.7) As established in Topic 3E, under the same conditions dG = dw Therefore, at constant temperature and pressure, add, max" dwana, uadna + Hodne + .
-
Introduction to Organic and Biochemistry
By William Henry Brown, Theodore E BrownIntroduction to Organic and Biochemistry