The present volume collects a total of 72 contributions presented to the International Symposium on Compact Heat Exchangers. Among them, one is the reprint of an interview to Rames made by Bill Begell and published on Heat Transfer Engineering about 22 years ago, and one is a 'laudatio' prepared by a colleague of Ramesh at Delphi Harrison Thermal Systems, where he spent most of his professional career. Seven keynote lectures highlight important topics for the development of compact heat exchangers: heat transfer and accuracy of thermal measurements, single-phase heat transfer and flow vaporization in microchannels, micro heat pipes, numerical methods for, enhanced boiling heat transfer, compact polymer heat exchangers. An excellent update in many aspects of compact heat exchangers; single-phase flow and heat transfer: (fundamental studies, design data and methods), single- and two-phase heat exchanger development and application, augmentation techniques, pressure drop, phase change heat transfer (fundamental studies, design data and methods).