Both autophagy and programmed cell death (PCD) are fundamental processes of cellular maintenance that are closely interrelated in plant and animal cells under physiological and stressful conditions. Differentiation, immune response, lack of nutrients, and wide range of abiotic factors induce their development and realisation of survival or cell death scenario. Microtubular cytoskeleton is known as one of the principle players in the mediation of PCD/autophagic signals. Chapter One in this book presents an overview of the current knowledge about the role of MTs in PCD- and autophagy-related processes in plants. Chapter Two reviews the mechanisms and consequences of virus interactions with the hotel cell-death machinery, to help understand potentially pathologically relevant consequences that will help in the design of intervention strategies and the development of antiviral therapies. The final chapter discusses the control of the levels of different reactive oxygen species (ROS) and their interaction with hormones and transcriptional factors in relation with programmed cell death in leaves.
... and anti - apoptotic genes such as Bcl - 2 , Bcl - XL , X - linked inhibitor of apoptosis ( for a review , see Burstein and Duckett , 2003 ) . Therefore , one prevailing model proposes that when the molecular ratio of pro - survival ...
Neuronal Cell Apoptosis
V. , Dee , L. , Olson . J. . Uretz , E. , and Parrillo , J. E. , ( 1996 ) . Tumor Necrosis Factor alpha and Interleukin l beta Are Responsible for In Vitro Myocardial Cell Depression Induced by Human Septic Shock Serum .
Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain . Proc Natl Acad Sci US A. 2003 ; 100 ( 15 ) : 9023-7 . Epub 2003 Jul 9 . [ 73 ] Vis JC , Schipper E , de Boer - van Huizen RT , Verbeek MM ...
While up-regulation of this pathway has been associated with increased cellular proliferation and invasion (Mimeault, Pommery, and Henichart, 2003), its role in prostate cancer therapeutic resistance and androgen-independent status is ...
Abstract: Endoplasmic reticulum (ER) stress is a form of cellular stress that is experienced both under normal physiological conditions such as in professional secretory cells and disease states such as cancer, diabetes and ...
Apoptosis examines how the process of cell suicide (apoptosis) is regulated, and how our understanding of this process may lead to novel treatments for a wide variety of human diseases.
Compiling the most recent research results on the relationship between apoptosis and cancer in one handy volume, this book will provide a valuable reference for scientists working in cancer research as well as newcomers to the field.
It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This book presents research from around the world.
Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body's defence mechanisms against disease.