Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.
This book, a compilation by experts in the field, is designed to provide an introduction to the area of medicinal inorganic chemistry and to summarize current, state-of-the-art developments in the...
Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as ...
Sivaraja , M. , Goodin , D. B. , Smith , M. , and Hoffman , B. M. , “ Identification by ENDOR of Trp191 as the free - radical site in cytochrome - c peroxidase compound ES ” , Science , 245 , 738-740 ( 1989 ) . 26.
This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application ...
This book provides a contemporary research-led overview of the applications of inorganic materials in biomedicine.
About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work.
The book is intended for use by undergraduate students of pharmacy .
Excerpt from Text-Book of Chemistry: Inorganic and Organic With Toxicology, for Students of Medicine, Pharmacy, Dentistry and Biology In the preface to the earlier editions of this book the author clearly specified its scope and purpose.
Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine.
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations.