Fast Facts: Chronic Lymphocytic Leukemia

Fast Facts: Chronic Lymphocytic Leukemia
ISBN-10
3318072303
ISBN-13
9783318072303
Series
Fast Facts
Category
Medical
Pages
80
Language
English
Published
2023-06-07
Publisher
Karger Medical and Scientific Publishers
Authors
Parag Jasani, Toby A. Eyre, Lindsey E. Roeker

Description

Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. Table of Contents • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

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