Hepatitis C Virus: From Molecular Virology to Antiviral Therapy

Hepatitis C Virus: From Molecular Virology to Antiviral Therapy
ISBN-10
3642273408
ISBN-13
9783642273407
Category
Medical
Pages
346
Language
English
Published
2013-03-12
Publisher
Springer Science & Business Media
Author
Ralf Bartenschlager

Description

Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.

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