The first to combine both the bioinorganic and the organometallic view, this handbook provides all the necessary knowledge in one convenient volume.
The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired ...
The book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.
(a) Tice,C. M. Selectingthe right compounds for screening: Does Lipinski's Rule of5for pharmaceuticals apply to agrochemicals? Pest.Manag. Sci., 2001, 57, 3–16. (b) Tice, C.M. Selecting the right compounds for screening: Useof ...
The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches.
Despite the intense efforts that go into the development and evaluation of novel methodologies and search tools, ... SBVS)3,4 and approaches that rely on structures of known active small molecules (ligand-based virtual screening, ...
Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition.
It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Focusing on validation methods, search algorithms, and scoring functions, this book is a pivotal resource for professionals, researchers, students, and practitioners in the field of theoretical and computational chemistry.
When I was a graduate student, I devised a screen to search for small molecules that could block the action of a specific protein, called TGFbeta (for transforming growth factor beta), which is involved in the formation of certain ...