Large DNA molecules > 50 kb ) become distorted as they move through the pores of an agarose gel . Because long DNAs " snake " through the gel , their mobility is essentially independent of their length . In a pulsed - field gel , the ...
An understanding of the initiation of DNA replication holds the key to what controls cell division, growth and differentiation. This topic is central to studies in biochemistry, cell biology, genetics...
This book reviews the latest trends and future directions of DNA replication research.
In spite of well established methodologies - which are also described in the book - the origin identification in mammalian chromosomes is still a controversial subject.
Many characteristics of this process show thorough conservation across organisms in all domains of life. This book outlines and reviews the present condition of knowledge on numerous crucial aspects of the DNA replication procedure.
Updated and revised, this thorough volume covers a range of methods focusing on systems, including mammalian, yeast, bacterial and archaeal.