This volume provides and educative and authoriative discussions on the drug discovery and development process. It is divided into ten sections and starts with personal recollections on the history and...
This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include CNS diseases (schizophrenia, anxiety, Alzheimer's), Pain, Metabolic...
Computer-assisted Drug Design (CADD) reviews the use of computational methods and how these can aid the drug discovery process. Experts review in-silico approaches for the design and improvement of drug...
Reviews the important technologies used in each step of the drug discovery process; target search, target validation, informatics and databases, structural biology, screening, chemical technologies, and lead search and optimization....
This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include Cancer (biology, chemotherapy, mechanism & target approaches),...
Presents a different view of medicinal chemistry through personal accounts by eminent scientists describing their lifetime experiences in the field. Also illustrates 14 case studies of successful drug discovery and...
We therefore decided to evaluate future analogs as pure P1 isomers. ... We therefore decided to investigate new P10 derivatives of analog 74 that lacked double bond and made new analogs as a single diastereomer at P1 (Table 13).
To be effective a drug must be Absorbed then Distributed to the site of action. It must also be Metabolised and Excreted without any measurable Toxicity (ADMET). This volume examines...
Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, ...