Three-Dimensional Electron Microscopy of Macromolecular Assemblies

Three-Dimensional Electron Microscopy of Macromolecular Assemblies
ISBN-10
0080525814
ISBN-13
9780080525815
Series
Three-Dimensional Electron Microscopy of Macromolecular Assemblies
Category
Science
Pages
342
Language
English
Published
1996-01-24
Publisher
Elsevier
Author
Frank Joachim

Description

Three-Dimensional Electron Microscopy of Macromolecular Assemblies is the first systematic introduction to single-particle methods of reconstruction. It covers correlation alignment, classification, 3D reconstruction, restoration, and interpretation of the resulting 3D images in macromolecular assemblies. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods. Key Features * Presents methods that offer an alternative to crystallographic techniques for molecules that cannot be crystallized * Describes methods that have been instrumental in exploring the three-dimensional structure of * the nuclear pore complex * the calcium release channel; * the ribosome * chaperonins

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