Animal Models for the Study of Human Disease: Chapter 28. Animal Models of Drug Abuse: Place and Taste Conditioning

Animal Models for the Study of Human Disease: Chapter 28. Animal Models of Drug Abuse: Place and Taste Conditioning
ISBN-10
0128072180
ISBN-13
9780128072189
Series
Animal Models for the Study of Human Disease
Category
Medical
Pages
1108
Language
English
Published
2013-05-29
Publisher
Elsevier Inc. Chapters
Author
Catherine M. Davis

Description

Preclinical animal research has contributed greatly to our understanding of numerous human disease states and will continue to provide a method for investigating the various biochemical events, physiological processes, and behavioral implications of various diseases. For substance abuse and dependence, this research has enabled scientists to gain a greater understanding of the neurochemical events involved in the brain's response to drugs, both licit and illicit, and to provide a means by which to design and test novel pharmaco-therapeutic interventions. To enable these discoveries, scientists have developed numerous animal models that attempt to replicate human drug addiction. The current review explores two popular Pavlovian conditioning procedures, conditioned place preference and conditioned taste aversion, which are used to investigate the rewarding and aversive effects (respectively) of drugs of abuse. For each procedure, a brief history of the field is followed by the advantages of the procedures and a step-by-step explanation of each procedure's conditioning protocol.

Other editions

Similar books