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Animal Models of Cholestasis Peter Fickert, Marion J. Pollheimer, Christoph H. Österreicher, Michael Trauner. 120. 121. 122. 123. 124. 125. 126. 127. ... J Clin Invest. 1998;101(10):2092–2100. Trauner M, Nathanson MH, Rydberg SA, et al.
In humans, the natural history of prostate cancer spans 30–40 years, which makes it a difficult disease to model in rodents.
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The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models ...
The constant increase in the number of obese and diabetic patients, which has become a concern of public health, is the consequence of dysregulations in energy homeostasis.
This is especially true in the advent of the Food and Drug Administration's animal rule.
The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models ...
Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy ...
To create and establish mutant mice as models for human diseases and traits, various forward and reverse genetics tools are currently available.
Identifying and selecting the most appropriate animal model is a challenge, but the U.S. Federal Government’s National Institutes of Health, has supported several efforts to make the job of finding disease models easier.
Genetically modified animals were created about 30 years ago, and are considered good models of human diseases.
Reward behavior represents a subset of conditioning procedures that have been developed by psychologists to study learning in animals.
This chapter reviews the insights obtained into studies into KS over the past decades and highlights the contribution made by the animal model.
In this review, we compare the salient anatomy of the primate and rodent retina, particularly in the light of AMD pathology. Next, prevailing hypotheses explaining how AMD may develop are discussed.
The current review explores two popular Pavlovian conditioning procedures, conditioned place preference and conditioned taste aversion, which are used to investigate the rewarding and aversive effects (respectively) of drugs of abuse.