Population Genomics in the Developing World: Concepts, Applications, and Challenges

Population Genomics in the Developing World: Concepts, Applications, and Challenges
ISBN-10
0443185476
ISBN-13
9780443185472
Category
Science
Language
English
Published
2024-03-01
Publisher
Elsevier
Authors
Marlo Möller, Caitlin Uren

Description

Population Genomics in the Developing World: Concepts, Applications, and Challenges, a new volume in the Translational and Applied Genomics series, provides a comprehensive, up-to-date summary of the field of populations genomics in developing countries. This book equips students, researchers, and clinicians with the practical skills and approaches necessary to face the unique challenges and opportunities of practicing population genomics in developing countries. Following a brief foundational overview, more than a dozen authors working in developing nations share applied case studies from the field, including rationale, methods, analysis, and outcomes to reinforce understanding. Key themes across the country specific chapters include efficient genetic data generation and effective computational and statistical tools to analyze population-level data. The book then discusses clinical interpretation of this data, from direct-to-consumer ancestry testing to translational and applied precision medicine. A final chapter considers ethical aspects of conducting genomic research in developing countries. Addresses the unique opportunities to positively impact global health by practicing population genomics in developing countries Features applied case studies from genomic research in various developing nations, with clear instruction in research rationale, methods, tools, materials used, analysis, and outcomes Includes international chapter authors and population genomics experts practicing in South Africa, Gabon, India, South America, Central America, and Honduras, among other locations

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