Neurotransmitter Transporters: Structure, Function, and Regulation

Neurotransmitter Transporters: Structure, Function, and Regulation
ISBN-10
1592594700
ISBN-13
9781592594702
Series
Neurotransmitter Transporters
Category
Medical
Pages
410
Language
English
Published
1996-10-01
Publisher
Springer Science & Business Media
Author
Maarten E. A. Reith

Description

A comprehensive survey of recent advances made in characterizing neurotransmitter transporters-including their imaging in the living brain-and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure-activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.

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