Science of Synthesis: Metal-Catalyzed Cyclization Reactions

Science of Synthesis: Metal-Catalyzed Cyclization Reactions
ISBN-10
3131999012
ISBN-13
9783131999016
Series
Science of Synthesis
Category
Science
Pages
805
Language
English
Published
2016-12-14
Publisher
Georg Thieme Verlag
Authors
Shuanhu Gao, Shengming Ma

Description

Significant advances in metal-catalyzed reactions, especially cyclizations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date these transformations are widely used in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: Metal-Catalyzed Cyclization Reactions" presents the most commonly used and significant metal-catalyzed reactions for modern organic synthesis. The basic principles, the current state of the art, scope, limitations, and mechanism of these reactions are also discussed. Typical examples of target synthesis are provided to help inspire further applications. Volume 1 covers intramolecular coupling reactions (including Heck reactions), intramolecular allylations, and cyclopropane and cyclopropene ring openings. Also included are cyclization reactions of alkenes, alkynes, and allenes, cycloisomerizations, and intramolecular C-N and C-O bond formation.

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