Diet, immunity and inflammation: 1. Innate and adaptive immunity

Diet, immunity and inflammation: 1. Innate and adaptive immunity
ISBN-10
0128086939
ISBN-13
9780128086933
Series
Diet, immunity and inflammation
Category
Medical
Pages
760
Language
English
Published
2013-09-30
Publisher
Elsevier Inc. Chapters
Authors
P.S. Noakes, L.J. Michaelis

Description

The innate and adaptive immune systems are often described as contrasting separate arms of the host response; however, they usually act together, with the innate response representing the first line of host defense and the adaptive response becoming prominent after several days as antigen-specific T and B cells have undergone clonal expansion. Components of the innate system contribute to activation of the antigen-specific cells. Additionally, the antigen-specific cells amplify their responses by recruiting innate effector mechanisms to bring about the complete control of invading microbes. Thus, although the innate and adaptive immune responses are fundamentally different in their mechanisms of action, synergy between them is essential for an intact, fully effective immune response.

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