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Although inflammation is one of the body’s first responses to infection, overactive immune responses can cause chronic inflammatory diseases. Long-term low-grade inflammation has also been identified as a risk factor for other diseases.
This chapter discusses the role of vitamin D in the regulation of the immune system.
The chapter begins by discussing the impact of intensive exercise training on immune function and susceptibility to infection in athletes.
For several decades the incidence and prevalence of chronic inflammatory diseases have been increasing, particularly in westernized countries.
The intestinal immune system has generated two arms of adaptive anti-inflammatory defense which normally preserve the epithelial barrier: (i) immune exclusion performed by secretory IgA (SIgA) (and SIgM) antibodies to control surface ...
Vitamin A is required in the diet of all vertebrates, and is metabolized intracellularly to retinoic acid (RA), which is well known as a regulator of cell proliferation and differentiation.
Animal studies suggest that olive oil modulates immune function in vivo and ex vivo when fed at high levels.
The increasing prevalence of immune-mediated adverse reactions to food represents a significant personal and societal burden.
Selenium (Se) is an essential micronutrient that is important for various aspects of human health, including optimal immune responses.
The human gut is the natural habitat for a diverse and dynamic microbial ecosystem having an important impact on health and disease.
The intestinal microbiota and some probiotics are known to interact with the host’s immune system, thereby influencing both health status and disease risk.
In addition to nutrients affecting chronic low-grade inflammation, dietary patterns and specific foods significantly modulate inflammatory processes.
Short-chain fatty acids (SCFAs) are the main metabolic products of anaerobic bacterial fermentation in the intestine.
In addition to supplying essential nutrients, it is now well accepted that some food proteins can confer additional health benefits beyond nutrition.
It has been suggested that flavonoids, secondary metabolites widely present in the vegetable kingdom, are involved in the role played by plant foods in disease prevention.
This chapter deals with the overall age-associated changes observed in human immunity, beginning with an overview of the components of the immune system.
L-Arginine (Arg) was traditionally classified as a nutritionally non-essential amino acid for infant and adult humans; however, it is now known that besides serving as a building block for protein, it plays an essential role in the ...
The innate and adaptive immune systems are often described as contrasting separate arms of the host response; however, they usually act together, with the innate response representing the first line of host defense and the adaptive response ...
Iron is required for many biochemical reactions of immune and non-immune cells, and pathogens.