Diet, immunity and inflammation: 7. The role of iron in immunity and inflammation: implications for the response to infection
- ISBN-10
- 0128086998
- ISBN-13
- 9780128086995
- Series
- Diet, immunity and inflammation
- Category
- Medical
- Pages
- 760
- Language
- English
- Published
- 2013-09-30
- Publisher
- Elsevier Inc. Chapters
- Authors
- S.R. Kuvibidila, S.B. Baliga, L.C. Chandra
Description
Iron is required for many biochemical reactions of immune and non-immune cells, and pathogens. Iron deficiency remains a worldwide public health problem in children and women of childbearing age. Iron overload is common in individuals with genetic disorders of proteins involved in iron metabolism. The influence of iron homeostasis on the immune function and risk of infection has been recognized since the 1970s. Recent discoveries have shed light on the various proteins that modulate iron metabolism and their role in immunity. This chapter summarizes our current knowledge on the mechanisms by which iron dysregulation alters the immune response and the conflicting results relating to its effect on risk of infection.
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Other editions
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
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