Diet, immunity and inflammation: 8. Vitamin A and the immune system
- ISBN-10
- 0128087005
- ISBN-13
- 9780128087008
- Series
- Diet, immunity and inflammation
- Category
- Medical
- Pages
- 760
- Language
- English
- Published
- 2013-09-30
- Publisher
- Elsevier Inc. Chapters
- Authors
- A.C. Ross, K.H. Restori
Description
Vitamin A is required in the diet of all vertebrates, and is metabolized intracellularly to retinoic acid (RA), which is well known as a regulator of cell proliferation and differentiation. RA activates nuclear retinoid receptors and regulates a wide variety of genes. This chapter first discusses vitamin A nutrition and metabolism, and then how inflammation affects the metabolism of vitamin A compounds. Clinically, RA and several analogs are used in the treatment of skin disorders. Vitamin A deficiency is a risk factor for infectious disease. This chapter discusses the role of vitamin A in the immune system, especially in the regulation of T cell differentiation and in innate immunity.
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Other editions
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- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
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