Diet, immunity and inflammation: 11. Impacts of prebiotics on the immune system and inflammation

Diet, immunity and inflammation: 11. Impacts of prebiotics on the immune system and inflammation
ISBN-10
012808703X
ISBN-13
9780128087039
Series
Diet, immunity and inflammation
Category
Medical
Pages
760
Language
English
Published
2013-09-30
Publisher
Elsevier Inc. Chapters
Author
F. Guarner

Description

The human gut is the natural habitat for a diverse and dynamic microbial ecosystem having an important impact on health and disease. Unabsorbed portions of food are a major nutritional source for these microbial communities. Prebiotics are non-digestible food ingredients that are selectively fermented in the gut resulting in specific changes in the composition or activity of the gastrointestinal microbiota, thus conferring benefits upon host health. Inulin-type fructans and galacto-oligosaccharides are the most extensively studied prebiotics. They are fermented in the colon to short-chain fatty acids, and selectively stimulate the growth of bifidobacteria. These changes have an impact on the mucosal and systemic immune system and are correlated with a series of health benefits reviewed in this chapter.

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