Diet, immunity and inflammation: 25. The immune system during ageing
- ISBN-10
- 012808717X
- ISBN-13
- 9780128087176
- Series
- Diet, immunity and inflammation
- Category
- Medical
- Pages
- 760
- Language
- English
- Published
- 2013-09-30
- Publisher
- Elsevier Inc. Chapters
- Authors
- L. Müller, G. Pawelec, E. Derhovanessian
Description
This chapter deals with the overall age-associated changes observed in human immunity, beginning with an overview of the components of the immune system. We then summarize the effects of age on these different components, discussing the problems faced by investigators studying ageing in long-lived outbred species like humans. We describe the limitations inherent in cross-sectional studies together with some possible solutions to these problems, such as longitudinal studies. We then discuss the possible reasons for these age-associated changes, starting with hematopoiesis and the effects of age on stem cells and continuing with the phenomenon of thymic involution. We consider biomarkers termed ‘immune signatures’ and those forming an ‘immune risk profile’. We conclude with a brief consideration of overall impact of age on responses to vaccination in humans.
Get the book
Other editions
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
-
- 2013-09-30
- 760 pages
- Ebook
- Elsevier Inc. Chapters
Similar books
-
How Institutions are Shaping the Future of Our Children: For Better or for Worse?
By Catherine Dulmus, Karen SowersLammert, M., & Timberlake, E. M. (1986). Termination of foster care for the older adolescent: Issues of emancipation and individuation.
-
Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity
By William J. Rea, Kalpana D. PatelDou, L., E. Bertrand, C. Cerini, V. Faure, J. Sampol, R. Vanholder, Y. Berland, P. Brunet. ... A. Timberlake, B. Sumpio, R. Pfragner, I. M. Modlin, M. Kidd.
-
Rockwood and Green's Fractures in Adults
By William Ricci, Charles M. Court-Brown, Margaret M. McQueenChendrasekhar A, Moorman DW, Timberlake GA. An evaluation of the effects of ... Chittiboina P, Wylen E, Ogden A, et al. Traumatic spondylolisthesis of the ...
-
Breast Pathology, An Issue of Surgical Pathology Clinics
By Laura C. CollinsHartmann LC, Radisky DC, Frost MH, et al. Understanding the premalignant potential of ... D'Alfonso TM, Wang K, Chiu YL, et al. Pathologic upgrade rates on ...
-
Telepractice in Speech-Language Pathology
By K. Todd HoustonStensland, J., Speedie, S., Ideker, M., House, J., & Thompson, T. (1999). The relative cost of outpatient ... Deal, J. L. (1987). Appraisal and diagnosis of ...
-
Addressing Adversity: Prioritising adversity and trauma-informed care for children and young people in England.
By Marc Bush, Lord Victor Adebowale, Rebecca Adlington1 2 Howard, S. and Johnson, B. (2000) Resilient and Non-resilient Behaviour in ... 4 De Haan, L., Hawley, D. and Deal, J. (2002) 'Operationalizing family ...
-
Culture, Brain, and Analgesia: Understanding and Managing Pain in Diverse Populations
By Mario Incayawar, Knox H. Todd... are not fluent in the language/s of the medical care provider.72 Research ... Anglo-Americans have traditionally placed a great deal of emphasis on the ...
-
Image-Guided Spine Interventions
By John M. MathisThis practical guide thoroughly discusses both well-established and new interventions that are applied to the spine for the purpose of pain relief.
-
New Mynursinglab -- Access Card -- For Maternal-Child Nursing (24-Month Access)
By Pearson Education, Pearson Education, Inc., David P Pearson EducationSeveral versions of Pearson's MyLab & Mastering products exist for each title, including customized versions for individual schools, and registrations are not transferable.
-
Pearson's Medical Assisting (General)
By Pearson Education Staff, Madan Dr Pearson EducationIf a picture paints a thousand words, imagine what video can do? Pearson Medical Assisting Videos help users learn the nuances and the details of many medical assisting procedures.